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COBRA CARDIOTOXIN PROTEINS
Descriptors Found:
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DeCS
Descriptor
English
:
Cobra Cardiotoxin Proteins
Descriptor
Spanish
:
Proteínas Cardiotóxicas de Naja
Descriptor
Portuguese
:
Proteínas Cardiotóxicas de Naja
Synonyms
English
:
Cobra Cardiotoxin
Direct Lytic Factors
Tree Number:
D12.776.831.222
D20.888.850.325.220.260
D23.946.833.850.325.220.260
Definition
English
:
Most abundant
proteins
in
COBRA
venom; basic polypeptides of 57 to 62
amino acids
with four disulfide bonds and a
molecular weight
of less than 7000; causes skeletal and cardiac
muscle contraction
, interferes with neuromuscular and ganglionic transmission, depolarizes nerve, muscle and
blood
cell
membranes
, thus causing
hemolysis
.
Indexing Annotation
English
:
/antag permitted but consider also
ANTIVENINS
History Note
English
:
2008(1978)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
4239
Unique Identifier:
D004179
Occurrence in VHL
:
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